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🔍 What is the CSF Lactate Test?

The Cerebrospinal Fluid (CSF) Lactate Test measures the lactate levels in the CSF—the fluid surrounding the brain and spinal cord. Lactate is a byproduct of glucose metabolism, and its elevated levels can indicate brain infections, oxygen deprivation, or neurological disorders.

🎯 Purpose of the Test

  • Differentiate between bacterial & viral meningitis
  • Detect brain hypoxia (oxygen deprivation)
  • Diagnose neurological disorders like mitochondrial diseases
  • Monitor brain infections & metabolic conditions

📊 Normal Ranges & Interpretation (May vary by lab method)

Age GroupNormal CSF Lactate Range (mmol/L)
Adults & Children1.2 – 2.1 mmol/L
Newborns1.1 – 3.0 mmol/L

🔺 High CSF Lactate Levels May Indicate:

  • Bacterial, fungal, or tuberculous meningitis
  • Brain hypoxia (stroke, trauma, cardiac arrest)
  • Seizures or mitochondrial disorders

🔻 Low CSF Lactate Levels: Usually not concerning but could indicate metabolic issues in rare cases.

📝 Additional Testing May Include:

  • CSF Glucose & Protein Tests (To assess infection or inflammation)
  • Blood Lactate Test (To compare systemic vs. CSF lactate levels)
  • Lumbar Puncture (Spinal Tap) (To collect CSF sample for further analysis)
  • MRI or CT Scan (For structural brain abnormalities)

👩‍⚕️ When Should You Get Tested?

  • Symptoms of meningitis (fever, stiff neck, severe headache, confusion)
  • Seizures or unexplained neurological symptoms
  • After a stroke, head trauma, or cardiac arrest
  • Suspicion of mitochondrial or metabolic disorders

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  • You don't need any special preparation for this test.

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