📌 What is the Islet Cell Antibody (ICA) Test?
A blood test that detects autoantibodies targeting pancreatic islet cells, which produce insulin.
Used to identify autoimmune destruction of insulin-producing cells, commonly seen in Type 1 Diabetes Mellitus (T1DM).
Helps predict the risk of developing T1DM in at-risk individuals.
🎯 Purpose of the Test
✅ Diagnoses Type 1 Diabetes in newly diagnosed diabetic patients.
✅ Identifies autoimmune diabetes (Latent Autoimmune Diabetes in Adults - LADA).
✅ Helps assess risk in family members of Type 1 diabetics.
📊 Normal Ranges & Interpretation
🔹 Normal Result: No detectable islet cell antibodies (Negative result).
🔹 Abnormal Result: Presence of islet cell antibodies (Positive result), indicating an increased risk or presence of Type 1 Diabetes.
Higher antibody levels suggest greater beta-cell destruction.
📝 Test Procedure
1️⃣ A blood sample is collected.
2️⃣ The sample is analyzed using immunofluorescence or enzyme-linked immunosorbent assay (ELISA).
3️⃣ Results help detect the presence of islet cell antibodies.
⚠️ Who Should Get Tested?
🔹 Individuals with symptoms of Type 1 Diabetes, such as:
Excessive thirst & urination
Unexplained weight loss
Fatigue & blurred vision
🔹 People with a family history of Type 1 Diabetes to assess risk.
🔹 Adults with suspected Latent Autoimmune Diabetes (LADA).
✅ Why is This Test Important?
✔️ Early detection of autoimmune diabetes before severe symptoms develop.
✔️ Helps distinguish Type 1 Diabetes from Type 2 Diabetes.
✔️ Aids in disease monitoring and treatment planning.