What is the ACE Test?
The Angiotensin-Converting Enzyme (ACE) test measures the level of ACE enzyme in the blood. ACE plays a role in blood pressure regulation but is also linked to sarcoidosis, a disease that causes inflammation and granulomas (small clusters of immune cells) in the body.
Normal Range:
Adults: 8 – 53 U/L (Varies by laboratory)
Elevated ACE Levels: May suggest sarcoidosis or other inflammatory diseases.
Decreased ACE Levels: Can be due to ACE inhibitor medications used for high blood pressure.
(Reference values may vary depending on laboratory methods)
Purpose of the Test:
✅ Diagnose & Monitor Sarcoidosis – Helps detect granulomas in the lungs, lymph nodes, and other organs.
✅ Evaluate Lung & Autoimmune Disorders – High ACE levels can be linked to tuberculosis, leprosy, and other chronic diseases.
✅ Assess Response to Sarcoidosis Treatment – Tracks ACE levels to see if treatment is effective.
✅ Differentiate Between Conditions – Helps rule out other causes of inflammation or lung disease.
What Can Affect ACE Test Results?
🔹 Elevated ACE Levels: May indicate sarcoidosis, tuberculosis, or chronic inflammation.
🔹 Low ACE Levels: Could be due to ACE inhibitors, steroids, or genetic conditions.
🔹 Not Definitive for Diagnosis: High ACE levels alone do not confirm sarcoidosis, and other tests (like chest X-rays or biopsies) may be needed.
How is the Test Performed?
A blood sample is drawn and analyzed in a laboratory.
📌 When to Get Tested? If experiencing persistent cough, shortness of breath, fatigue, enlarged lymph nodes, or suspected sarcoidosis.