📌 What is the ANA / ENA Blot Profile Test?
A qualitative blood test used to detect antinuclear antibodies (ANA) and specific extractable nuclear antigens (ENA) associated with autoimmune diseases.
📊 Normal Result
✔ Negative (No detectable ANA or ENA antibodies)
🚨 Abnormal (Positive) Result
❌ Positive results may indicate the presence of autoimmune diseases such as:
Systemic Lupus Erythematosus (SLE)
Sjögren’s Syndrome
Mixed Connective Tissue Disease (MCTD)
Scleroderma
Polymyositis/Dermatomyositis
🎯 Purpose of the Test
✅ Helps diagnose autoimmune conditions
✅ Identifies specific antibodies to determine disease type
✅ Monitors disease progression and treatment effectiveness
💡 Key Facts
🔹 ANA Test screens for general autoimmune activity
🔹 ENA Panel identifies specific antibodies (e.g., anti-Ro, anti-La, anti-Sm, anti-RNP)
🔹 Positive results require further clinical correlation and additional testing