🦠 What is the Test?
The AFB (Acid-Fast Bacilli) Sensitivity Test for Kanamycin determines whether Mycobacterium tuberculosis (TB bacteria) is resistant or susceptible to kanamycin, an injectable second-line antibiotic used in the treatment of drug-resistant tuberculosis (MDR-TB & XDR-TB).**
📊 Normal Ranges:
Susceptible (S) → TB bacteria respond to kanamycin (effective treatment).
Resistant (R) → TB bacteria do not respond to kanamycin (alternative treatment needed).
Intermediate (I) → Partial response; may require dose adjustment or alternative drugs.
(Results may vary depending on laboratory testing methods.)
🎯 Purpose of the Test:
✅ Determines if kanamycin is effective in treating drug-resistant TB
✅ Helps guide treatment for multi-drug resistant tuberculosis (MDR-TB) and extensively drug-resistant TB (XDR-TB)
✅ Prevents ineffective antibiotic use and further resistance
✅ Assists in customizing TB treatment regimens
🩺 When is it Recommended?
🔹 Patients with MDR-TB or XDR-TB
🔹 Individuals with TB not responding to first-line antibiotics
🔹 High-risk patients with prior TB treatment or immunocompromised conditions
🔹 To determine appropriate second-line antibiotic therapy
📝 How is the Test Done?
A sputum, tissue, or body fluid sample is collected.
The bacteria are cultured in a lab and tested against kanamycin.
Results may take several weeks due to the slow growth of TB bacteria.
⚠️ What Do Abnormal Results Mean?
📉 Susceptible (S) → Kanamycin can be used as part of the TB treatment.
📈 Resistant (R) → Alternative second-line antibiotics should be considered.
🔍 Infographic Design Idea:
Medical-themed color scheme (blue, red, and white)
Illustration of TB bacteria with an antibiotic resistance test diagram
Simple chart for result interpretation (S, R, I)